[1,1'-Biphenyl]-4-acetic acid, α,α-dimethyl-, methyl ester - Names and Identifiers
| Name | [1,1'-Biphenyl]-4-acetic acid, α,α-dimethyl-, methyl ester
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| Synonyms | methyl 2-([1,1'-biphenyl]-4-yl)-2-methylpropanoate
[1,1'-Biphenyl]-4-acetic acid, α,α-dimethyl-, methyl ester
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| CAS | 81770-34-5
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[1,1'-Biphenyl]-4-acetic acid, α,α-dimethyl-, methyl ester - Physico-chemical Properties
| Molecular Formula | C17H18O2
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| Molar Mass | 254.33 |
| Density | 1.053±0.06 g/cm3(Predicted) |
| Boling Point | 352.4±11.0 °C(Predicted) |
[1,1'-Biphenyl]-4-acetic acid, α,α-dimethyl-, methyl ester - Introduction
Methyl 2-([1,1 '-biphenyl]-4-yl)-2-methylpropanoate is an organic compound with the chemical formula C21H20O2. It is a white crystalline solid which is soluble in organic solvents such as ethyl acetate or methanol at normal temperature.
For the use of this compound, it is mainly used as a pharmaceutical intermediate. It plays the role of connecting various functional groups in the synthesis of drugs, and is commonly used in the preparation of non-steroidal anti-inflammatory drugs and anti-tumor drugs.
The process for preparing methyl 2-([1,1 '-biphenyl]-4-yl)-2-methylpropanoate is generally carried out by an oxidation reaction. First, nitrosobenzene is reacted with phenylacetylene to form biphenyl, and then the present compound is obtained by oxidation reaction in the presence of oxygen.
For safety information, methyl 2-([1,1 '-biphenyl]-4-yl)-2-methylpropanoate may cause irritation to the eyes, skin and respiratory tract. Wear appropriate personal protective equipment during handling or use to avoid contact with skin, eyes or inhalation of vapors. Any work with the compound should be carried out in a well-ventilated area. If inhaled or exposed to the compound, rinse immediately with water and seek medical advice.
Last Update：2024-04-09 21:01:54